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The real weight of CACS

Cancer Anorexia-Cachexia Syndrome (CACS) is a common complication of cancer and has a profound impact on the clinical and personal history of the patient and the family. A major defining clinical feature of CACS is involuntary and progressive weight loss; scientific evidence supports a direct correlation between weight loss in cancer patients and negative effects on the antitumoral therapy. Loss of weight also correlates with decreased survival rates.

However, the impact of CACS on the patient is not just limited to the effect of weight loss. Quality of life, functional abilities, symptoms, psychological outcomes and also social aspects, are all affected by CACS.

Nowadays, the awareness of CACS as a definite clinical entity, worthy of being investigated, diagnosed and managed, is heterogeneously spread among health professionals and in some cases still represents an unmet need.

Egidio Del Fabbro, Jose M. Garcia, Jane Hopkinson

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