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STAT3 in the systemic inflammation of cancer cachexia

Zimmers TA, Fishel ML, Bonetto A.
Semin Cell Dev Biol. 2016 Feb 6. pii: S1084-9521(16)30051-9. doi: 10.1016/j.semcdb.2016.02.009. [Epub ahead of print]
Available at: www.ncbi.nlm.nih.gov

Presence of the tumor elicits an inflammatory response and profound metabolic derangements involving not only muscle and fat, but also the hypothalamus, liver, heart, blood, spleen and likely other organs. 

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